Khaled Aboshanab

  • Position

    Professor

  • Faculty

    Faculty of Pharmacy

  • Department

    Microbiology and Immunology

  • Fields of Interest

    Microbiology, Molecular Biotechnology, Immunology, Antibiotic Resistance, vaccinology

  • List of Publications

     (* =Corresponding author)

    A. International publications:

     

    Shaza M. Elhusseiny, Taghrid S. El-Mahdy, Nooran S. Elleboudy, Ibrahim S. Yahia, Mohamed M. S. Farag, Nasser S.M. Ismail, Mahmoud A. Yassien, Khaled M. Aboshanab*. In vitro Anti SARS-CoV-2 Activity and Docking Analysis of Pleurotus ostreatus, Lentinula edodes and Agaricus bisporus edible mushrooms. Infection and Drug Resistance 2022, (accepted. In Press).

    1. Abd-Allah IM, El-Housseiny GS, Alshahrani MY, El-Masry SS, Aboshanab KM*, Hassouna NA. An Anti-MRSA Phage From Raw Fish Rinse: Stability Evaluation and Production Optimization. Front Cell Infect Microbiol. 2022 May 17;12:904531. doi: 10.3389/fcimb.2022.904531. PMID: 35656033; PMCID: PMC9152141.
    2. Mostafa SH, Saleh SE, Hamed SM, Aboshanab KM*. Febrile illness of bacterial etiology in a public fever hospital in Egypt: High burden of multidrug resistance and WHO priority Gram negative pathogens. Germs. 2022 Mar 31;12(1):75-85. doi: 10.18683/germs.2022.1308. PMID: 35601951; PMCID: PMC9113693.
    3. El-Gayar MH, Ishak RAH, Esmat A, Aboulwafa MM, Aboshanab* KM. Evaluation of lyophilized royal jelly and garlic extract emulgels using a murine model infected with methicillin-resistant Staphylococcus aureus. AMB Express. 2022 Mar 21;12(1):37. doi: 10.1186/s13568-022-01378-x. PMID: 35312896; PMCID: PMC8938573.
    4. Kamel NA, Alshahrani MY, Aboshanab* KM, El Borhamy MI (2022). Evaluation of the BioFire FilmArray Pneumonia Panel Plus to the Conventional Diagnostic Methods in Determining the Microbiological Etiology of Hospital-Acquired Pneumonia. Biology (Basel). 2022 Feb 27;11(3):377. doi: 10.3390/biology11030377. PMID: 35336751; PMCID: PMC8945136..
    5. Elmesseri RA, Saleh SE, Elsherif HM, Yahia IS, Aboshanab KM* )2022). Staphyloxanthin as a Potential Novel Target for Deciphering PromisingAnti-Staphylococcus aureus Agents. Antibiotics (Basel), 11(3),298, https://doi.org/10.3390/antibiotics11030298
    6. Khalil WM, Aboshanab KM*, Aboulwafa MM (2022). Evaluation and Correlation of Rabies Vaccine Potency Using the National Institute of Health, Rapid Focus Fluorescent Inhibition, and Passive Hemagglutination Tests. Viral Immunol. 2022 Feb 1. doi: 10.1089/vim.2021.0181.. PMID: 35104162.
    7. Alshahawey MG, El-Housseiny GS, Elsayed NS, Alshahrani MY, Wakeel LM, Aboshanab KM*,. New insights on mucormycosis and its association with the COVID-19 pandemic. Future Sci OA. 2021 Dec 16;8(2):FSO772. doi: 10.2144/fsoa-2021-0122. PMID: 35059222; PMCID: PMC8686842.
    8. Kamel NA, Ismail NSM, Yahia IS, Aboshanab KM*. Potential Role of Colchicine in Combating COVID-19 Cytokine Storm and Its Ability to Inhibit Protease Enzyme of SARS-CoV-2 as Conferred by Molecular Docking Analysis. Medicina (Kaunas). 2021 Dec 23;58(1):20. doi: 10.3390/medicina58010020. PMID: 35056328.
    9. Eltokhy MA, Saad BT, Eltayeb WN, Yahia IS, Aboshanab KM*, Ashour MSE. Exploring the Nature of the Antimicrobial Metabolites Produced by Paenibacillus ehimensis Soil Isolate MZ921932 Using a Metagenomic Nanopore Sequencing Coupled with LC-Mass Analysis. Antibiotics (Basel). 2021 Dec 22;11(1):12. doi: 10.3390/antibiotics11010012. PMID: 35052889.
    10. El-Sayed SE, Abdelaziz NA, Osman HH, El-Housseiny GS, Aleissawy AE, Aboshanab KM*,. Lysinibacillus Isolate MK212927: A Natural Producer of Allylamine Antifungal 'Terbinafine'. Molecules. 2021 Dec 29;27(1):201. doi: 10.3390/molecules27010201. PMID: 35011429; PMCID: PMC8746802.
    11. Morgan RN, Saleh SE, Aboshanab KM*, M, Farrag HA. ADP-ribosyl transferase activity and gamma radiation cytotoxicity of Pseudomonas aeruginosa exotoxin A. AMB Express. 2021 Dec 22;11(1):173. doi: 10.1186/s13568-021-01332-3. PMID: 34936047; PMCID: PMC8695647.
    12. Eltokhy MA, Saad BT, Eltayeb WN, El-Ansary MR, Aboshanab KM*, Ashour MSE (2021). A Metagenomic Nanopore Sequence Analysis Combined with Conventional Screening and Spectroscopic Methods for Deciphering the Antimicrobial Metabolites Produced by Alcaligenes faecalis Soil Isolate MZ921504. Antibiotics (Basel). 10(11):1382. doi: 10.3390/antibiotics10111382. PMID: 34827320
    13. Mohammed MA, Salim MTA, Anwer BE, Aboshanab KM, Aboulwafa MM*(2021). Impact of target site mutations and plasmid associated resistance genes acquisition on resistance of Acinetobacter baumannii to fluoroquinolones. Sci Rep. 11(1):20136. doi: 10.1038/s41598-021-99230-y. PMID: 34635692; PMCID: PMC8505613
    14. Elshamy AA, Saleh SE, Alshahrani MY, Aboshanab KM*, Aboulwafa MM, Hassouna NA(2021). OXA-48 Carbapenemase-Encoding Transferable Plasmids of Klebsiella pneumoniae Recovered from Egyptian Patients Suffering from Complicated Urinary Tract Infections. Biology (Basel). 10(9):889. doi: 10.3390/biology10090889. PMID: 34571766; PMCID: PMC8469419
    15. Banoub NG, Sarra E Saleh, Hala S Helal, Khaled M Aboshanab* (2021). Antibiotics Combinations and Chitosan Nanoparticles for Combating Multidrug Resistance Acinetobacter baumannii. Infection and Drug Resistance 2021:14 3327–3339. https://doi.org/10.2147/IDR.S328788
    16. Elhusseiny, Shaza M., Taghrid S. El-Mahdy, Mohamed F. Awad, Nooran S. Elleboudy, Mohamed M.S. Farag, Khaled M. Aboshanab*, and Mahmoud A. Yassien (2021). "Antiviral, Cytotoxic, and Antioxidant Activities of Three Edible Agaricomycetes Mushrooms: Pleurotus columbinus, Pleurotus sajor-caju, and Agaricus bisporus" Journal of Fungi 7, no. 8: 645. https://doi.org/10.3390/jof7080645
    17. Elhusseiny SM, El-Mahdy TS, Awad MF, Elleboudy NS, Farag MMS, Yassein MA, Aboshanab KM* (2021). Proteome Analysis and In Vitro Antiviral, Anticancer and Antioxidant Capacities of the Aqueous Extracts of Lentinula edodes and Pleurotus ostreatus Edible Mushrooms. Molecules. 2021 Jul 30;26(15):4623. doi: 10.3390/molecules26154623. PMID: 34361776; PMCID: PMC8348442.
    18. Bishr AS, Abdelaziz SM, Yahia IS, Yassien MA, Hassouna NA, Aboshanab KM* (2021). Association of Macrolide Resistance Genotypes and Synergistic Antibiotic Combinations for Combating Macrolide-Resistant MRSA Recovered from Hospitalized Patients. Biology (Basel). 2021 Jul 6;10(7):624. doi: 10.3390/biology10070624. PMID: 34356479; PMCID: PMC8301042.
    19. Sakr MM, Elkhatib WF, Aboshanab KM*, Mantawy EM, Yassien MA, Hassouna NA (2021). In vivo evaluation of a recombinant N-acylhomoserine lactonase formulated in a hydrogel using a murine model infected with MDR Pseudomonas aeruginosa clinical isolate, CCASUP2. AMB Express. 2021 Jul 27;11(1):109. doi: 10.1186/s13568-021-01269-7. PMID: 34313869; PMCID: PMC8316526.
    20. Zaid ASA, Aleissawy AE, Yahia IS, Yassien MA, Hassouna NA, Aboshanab KM* (2021). Streptomyces griseus KJ623766: A Natural Producer of Two Anthracycline Cytotoxic Metabolites β- and γ-Rhodomycinone. Molecules. 2021 Jun 30;26(13):4009. doi: 10.3390/molecules26134009. PMID: 34209170; PMCID: PMC8271628..
    21. Abuzaid AS, Yassien MA, Aboshanab KM*, Elissawy AM (2021). Streptomyces variabilis isolate MW091521: A new microbial source of Heliomycin. Applied Biochemistry and Microbiology. 57(5), pp. 564–570. https://doi.org/10.1134/S0003683821050021
    22. Abd-Allah IM, El-Housseiny GS, Yahia IS, Aboshanab KM*, Hassouna NA (2021). Rekindling of a Masterful Precedent; Bacteriophage: Reappraisal and Future Pursuits. Front Cell Infect Microbiol. 2021 May 31;11:635597. doi: 10.3389/fcimb.2021.635597. PMID: 34136415; PMCID: PMC8201069..
    23. Noha A. Kamel, Lamia M. El Wakeel, Khaled M. Aboshanab* (2021) Exploring SARS-CoV-2 Spikes Glycoproteins for Designing Potential Antiviral Targets. (2021) Viral Immunol. 2021. doi: 10.1089/vim.2021.0023. PMID: 34018828.
    24. Reem Youssef, Ahmed Abass, Ahmed El-Shehawi, Mona Mabrouk, Khaled M. Aboshanab* (2021). Serotyping and antimicrobial resistance Profile of entericnontyphoidal Salmonella recovered from febrile neutropenic patients andpoultry in Egypt. Antibiotics (Basel). 2021 Apr 26;10(5):493. doi: 10.3390/antibiotics10050493. PMID: 33925773
    25. Kamel NA, Elsayed KM, Awad MF, Aboshanab KM*, El Borhamy MI. Multimodal Interventions to Prevent and Control Carbapenem-Resistant Enterobacteriaceae and Extended-Spectrum β-Lactamase Producer-Associated Infections at a Tertiary Care Hospital in Egypt. Antibiotics (Basel). 2021 Apr 30;10(5):509. doi: 10.3390/antibiotics10050509. PMID: 33946253; PMCID: PMC8146387.
    26. Abdelaziz SM, Aboshanab KM*, Yahia IS, Yassien MA, Hassouna NA. Correlation between the Antibiotic Resistance Genes and Susceptibility to Antibiotics among the Carbapenem-Resistant Gram-Negative Pathogens (2021) Antibiotics (Basel). 2021 Mar 4;10(3):255. doi: 10.3390/antibiotics10030255. PMID: 33806340; PMCID: PMC8001261.
    27. El-Housseiny GS, Ibrahim AA, Yassien MA, Aboshanab KM*.(2021).  Production and statistical optimization of Paromomycin by Streptomyces rimosus NRRL 2455 in solid state fermentation. BMC Microbiol. 2021 Jan 23;21(1):34. doi: 10.1186/s12866-021-02093-6. PMID: 33485318; PMCID: PMC7825151.
    28. Elsherif HM, Helal ZH, El-Ansary MR, Fahmy ZA, Eltayeb WN, Radwan S, Aboshanab KM*.(2020).  Staphylococcal Enterotoxins and Toxic Shock Syndrome Toxin-1 and Their Association among Bacteremic and Infective Endocarditis Patients in Egypt. Biomed Res Int. 2020 Dec 18;2020:6981095. doi: 10.1155/2020/6981095. PMID: 33381576; PMCID: PMC7762650.
    29. El-Housseiny GS*, Aboshanab KM, Aboulwafa MM, Hassouna NA. Structural and Physicochemical Characterization of Rhamnolipids produced by Pseudomonas aeruginosa P6. AMB Express. 2020 Nov 4;10(1):201. doi: 10.1186/s13568-020-01141-0. PMID: 33146788; PMCID: PMC7642061.
    30. El-Sayed SE, El-Housseiny GS, Abdelaziz NA, El-Ansary MR, Aboshanab KM*. (2020). Optimized Production of the Allylamine Antifungal "Terbinafine" by Lysinibacillus Isolate MK212927 Using Response Surface Methodology. Infect Drug Resist. 2020 Oct 15;13:3613-3626. doi: 10.2147/IDR.S267590. PMID: 33116681; PMCID: PMC7571585.
    31. El-Sayed SE, Abdelaziz NA, El-Housseiny GS, Aboshanab KM*.(2020).  Octadecyl 3-(3, 5-di-tert-butyl-4-hydroxyphenyl) propanoate, an antifungal metabolite of Alcaligenes faecalis strain MT332429 optimized through response surface methodology. Appl Microbiol Biotechnol. 2020 Dec;104(24):10755-10768. doi: 10.1007/s00253-020-10962-9. Epub 2020 Oct 22. PMID: 33090249.
    32. Mabrouk SS, Abdellatif GR, El-Ansary MR, Aboshanab KM*, Ragab YM. (2020). Carbapenemase Producers Among Extensive Drug-Resistant Gram-Negative Pathogens Recovered from Febrile Neutrophilic Patients in Egypt. Infect Drug Resist. 2020 Sep 11;13:3113-3124. doi: 10.2147/IDR.S269971. PMID: 32982326; PMCID: PMC7495499.
    33. Mohammed MA, Ahmed MT, Anwer BE, Aboshanab KM*, Aboulwafa MM. (2020). Propranolol, chlorpromazine and diclofenac restore susceptibility of extensively drug-resistant (XDR)-Acinetobacter baumannii to fluoroquinolones. PLoS One. 2020;15(8):e0238195. Published 2020 Aug 26. https://doi.org/10.1371/journal.pone.0238195
    34. Ann A. Elshamy, Khaled M. Aboshanab* (2020). A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options. Future Sciences OA.2020, 6(3). https://www.future-science.com/doi/10.2144/fsoa-2019-0098
    35. Ann A. Elshamy, Khaled M. Aboshanab*, Mahmoud A. Yassien, Nadia A. Hassouna (2020). Prevalence of Plasmid-mediated Resistance Genes Among Multidrug-Resistant Uropathogens in Egyp. African Health Sciences; 20(1):190-8. https://dx.doi.org/10.4314/ahs.v20i1.24
    36. Kamel NA, El-Tayeb WN, El-Ansary MR, Mansour MT, Aboshanab KM* (2019). XDR-Klebsiella pneumoniae isolates harboring blaOXA-48: In vitro and In vivo evaluation using a murine thigh-infection model. Experimental Biology and Medicine, 2019; 1-7 https://doi.org/10.1177/1535370219886826
    37.  Elsayed NS, Aboshanab KM*, Yassien MA, Hassouna NH.(2019). New insight into poly (3-hydroxybutyrate) production by Azomonas macrocytogenes isolate KC685000: large scale production, kinetic modeling, recovery and characterization. Molecular Biology Reports. 2019 Jun;46(3):3357-3370. https://doi.org/10.1007/s11033-019-04798-4
    38. Ibrahim AA, El-Housseiny GS, Aboshanab KM*,Yassien MA, Hassouna NA (2019). Paromomycin production from Streptomyces rimosus NRRL 2455: statistical optimization and new synergistic antibiotic combinations against multidrug resistant pathogens. BMC Microbiololgy 2019 Jan 18;19(1):18. doi: 10.1186/s12866-019-1390-1. https://doi.org/10.1186/s12866-019-1390-1
    39. El-Housseiny GS, Aboshanab KM*, Aboulwafa MM, Hassouna NA. (2019). Rhamnolipid production by a gamma ray-induced Pseudomonas aeruginosa mutant under solid state fermentation. AMB Express.;9(1):7. doi: 10.1186/s13568-018-0732-y. https://www.ncbi.nlm.nih.gov/pubmed/30617633
    40. Masarra M. Sakr, Khaled M. Aboshanab*, Walid F. Elkhatib, Mahmoud A. Yassien, Nadia A. Hassouna (2018). Overexpressed recombinant quorum quenching lactonase reduces the virulence, motility and biofilm formation of multidrug-resistant Pseudomonas aeruginosa clinical isolates. Applied Microbiology and biotechnology. DOI: 10.1007/s00253-018-9418-2
    41. Kamel NA, El-Tayeb WN, El-Ansary MR, Mansour MT, Aboshanab KM* (2018). Phenotypic screening and molecular characterization of carbapenemase-producing Gram-negative bacilli recovered from febrile neutropenic pediatric cancer patients in Egypt. PLoS One. 2018 A 29;13(8):e0202119. doi: 10.1371/journal.pone.0202119
    42. Elsayed NS, Aboshanab KM, Yassien MA*, Hassouna NA (2018). Kinetic modeling, recovery, and molecular characterization of poly-beta-hydroxybutyrate polymer in Acinetobacter baumannii isolate P39. Bioprocess Biosystem Engineering. doi: 10.1007/s00449-018-2000-6. PMID:30194493
    43. Samira M. Hamed, Walid F. Elkhatib*, Hadir A. El-Mahallawy, Mai M. Helmy, Mohamed S. Ashour,  Khaled M. A. Aboshanab (2018). Multiple mechanisms contributing to ciprofloxacin resistance among Gram negative bacteria causing infections to cancer patients. Scientific Reports, 16;8(1):12268. doi: 10.1038/s41598-018-30756-4. PMID:30115947
    44. Masarra M. Sakr, Khaled M. Aboshanab*, Walid F. Elkhatib, Mahmoud A. Yassien, Nadia A. Hassouna (2018). The effect of Ahl-1 recombinant lactonase on the resistance of Pseudomonas aeruginosa clinical isolates. World Journal of Pharmaceutical Sciences, 6(6): 101-106.http://www.wjpsonline.org/  
    45. Sally Tohamy Tohamy, Khaled Mohamed Aboshanab*, Hadir Ahmed El-Mahallawy, Mona R El-Ansary , Salwa Selim Afifi (2018). Prevalence of MDR Gram-negative Pathogens Isolated from Febrile Neutropenic Cancer Patients with Bloodstream Infections in Egypt and New Synergistic Antibiotic Combinations. Infection and Drug Resistance, 11:791–803. http://dx.doi.org/10.2147/IDR.S163293
    46. Ahmed MM, Aboshanab KM, Ragab YM, Missiakas DM, Aly KA* (2018). The transmembrane domain of the Staphylococcus aureus ESAT-6 component EssB mediates interaction with the integral membrane protein EsaA, facilitating partially regulated secretion in a heterologous host. Archives of Microbiology,. doi: 10.1007/s00203-018-1519-x. PMID: 29737367.
    47. Samira M. Hamed, Khaled M. A. Aboshanab*, Hadir A. El-Mahallawy, Mai M. Helmy, Mohamed S. Ashour, Walid F. Elkhatib (2018). Plasmid-Mediated Quinolone Resistance in Gram Negative Pathogens isolated from Cancer Patients in Egypt. Microbial Drug Resistance 2018; https://doi.org/10.1089/mdr.2017.0354
    48. Mansour NM*, Elkhatib WF, Aboshanab KM, Bahr MMA (2018). Inhibition of Clostridium difficile in Mice Using a Mixture of Potential Probiotic Strains Enterococcus faecalis NM815, E. faecalis NM915, and E. faecium NM1015: Novel Candidates to Control C. difficile Infection (CDI). Probiotics Antimicrob Proteins. doi: 10.1007/s12602-017-9285-7. (pp 1-12) https://www.ncbi.nlm.nih.gov/pubmed/28497217
    49. Ahmed Said Abu Zaid, Khaled M. Aboshanab*, Mahmoud Abdel Magead Yassin, Nadia Abdel-Haleim Hassouna (2017). Purification and Structure Elucidation of Potential Cytotoxic Agents from Streptomyces parvus KJ623765. World J Pharm Sci 2017; 5(12): 149-161 file:///C:/Users/khaled/Documents/Downloads/RT0WXH.pdf

     

    1. Noha S. Elsayed, Khaled M. Aboshanab*, Mahmoud A. Yassien, Nadia A.Hassouna (2017). Recovery and molecular characterization of poly-β-hydoxybutyrate polymer by Bacillus cereus isolate P83. World J Pharm Sci 2017; 5(9): 237-249 file:///C:/Users/khaled/Documents/Downloads/8jCgHa.pdf
    2. Hala A Farrag*, Mohamed M Aboulwafa , Khaled M Aboshanab, Amira A Abdelbaset1 (2017). Serum IL-6, IL-8 and CRP as Markers for Prediction of Bacteremia by Gram Negative Rods in Febrile Cancer Patients and in Irradiated Rats. J Medical Microbiology and Diagnosis. 6: 3, DOI: 10.4172/2161-0703.1000258. https://pdfs.semanticscholar.org/6270/b8134f45da13ca4a26a522d680d8432438f5.pdf
    3. Abdelkader MM, Aboshanab KM*, El-Ashry MA, Aboulwafa MM  (2017). Prevalence of MDR pathogens of bacterial meningitis in Egypt and new synergistic antibiotic combinations. PLoS One. 2017 Feb 16;12(2):e0171349. doi: 10.1371/journal.pone.0171349.https://www.ncbi.nlm.nih.gov/pubmed/28207768
    4. Ahmad M. Abbas, Khaled M. Aboshanab, Walid F. Elkhatib, Mohammad M. Aboulwafa*, Nadia A. Hassouna (2017). Improvement of Bioconversion of Vitamin D3 into Calcitriol by Actinomyces hyovaginalis through Protoplast Fusion and Enzyme Immobilization. International Journal of Biotechnology for Wellness Industries, 6 (1):32-40 http://www.lifescienceglobal.com/pms/index.php/ijbwi/article/view/4595
    5. Ghadir S. El-Housseiny, Khaled M. Aboshanab*, Mohammad M. Aboulwafa, Nadia A. Hassouna (2017). Isolation, screening and improvement of rhamnolipid production by Pseudomonas isolates. Indian Journal of Biotechnology (2017): 16(4): 611-619.
    6. Ayaa S.M. Hashim, Khaled M.A.Aboshanab, Aly F.M.El-Sayed* (2016). Developing an inactivated Rotavirus vaccine and evaluating the immunogenicity against a commercially available attenuated RV vaccine using a mice animal model. Viral immunology 29(10): 565-571. DOI: 10.1089/vim.2016.0073.http://online.liebertpub.com/doi/abs/10.1089/vim.2016.0073
    7. Ghadir S. El-Housseiny1 • Mohammad M. Aboulwafa*, Khaled M. Aboshanab, Nadia A. Hassouna (2016). Optimization of Rhamnolipid Production by P. aeruginosa Isolate P6.  Journal of surfactants and detergents 10: DOI: 10.1007/s11743-016-1845-4. https://link.springer.com/article/10.1007/s11743-016-1845-4
    8. Mona H. El-Gayar, Khaled M. Aboshanab*, Mohammad M. Aboulwafa, Nadia A. Hassouna (2016). Antivirulence and wound healing effects of royal jelly and garlic extract for the control of MRSA skin infections. Wound Medicine 13:18–27. http://dx.doi.org/10.1016/j.wndm.2016.05.004.
    9. Noha S. Elsayed, Khaled M. Aboshanab*, Mohammad M. Aboulwafa, Nadia A. Hassouna (2016). Cost-effective production of the bio-plastic poly-β-hydroxybutyrate using Acinetobacter baumannii isolate P39. Journal of Microbiology, Biotechnology and Food sciences. 5(6):552-556.  doi: 10.15414/jmbfs.2016.5.6.552-556.
    10. Sarra E. Saleh, Khaled M. Aboshanab*, Mohammad M. Aboulwafa and Nadia A. Hassouna (2015). Effects of plasmid acquisition by Pseudomonas aeruginosa clinical isolates on methicillin-resistant Staphylococcus aureus biofilm formation. African Journal of Microbiology research. 9(48): 2307-2319. DOI: 10.5897/AJMR2015.7789
    11. Aboshanab*, Khaled M, Elshafey Mostafa M (2015) Isolation and sequence analysis of a putative MerR-type-transcriptional regulator and a multidrug efflux protein of Bacillus circulans ATCC 21588: as potential targets of therapeutics. International Journal of Genetics and Molecular biology. 7(3): 15-24. DOI: 10.5897/ IJGMB2015.0112.
    12. Masarra Mohammed Sakr, Mohammad Mabrouk Aboulwafa, Khaled Mohamed Anwar Aboshanab*, Nadia Abdel-Haleem Hassouna (2015) Characterization of the quorum quenching activity of Streptomyces minutiscleroticus: A new approach for infection control. African Journal of Microbiology research. 9(8):492-502. DOI:10.5897/AJMR2014.7316
    13. Abdelaziz, Salma, Aboshanab*, Khaled M., Aboulwafa, Mohammad M., Hassouna, Nadia A (2015) Antimicrobial resistance pattern of some bacterial pathogens involved in lower respiratory tract infections in Egypt. Acta Microbiologica, 6(1:1), DOI 10.3823/286
    14. El-Gayar, Mona., Aboulwafa, Mohammad M., Aboshanab*, Khaled M.,  Hassouna, Nadia A (2014) Virulence characters of some methicillin resistant Staphylococcus aureus isolate. Archives of Clinical Microbiology, 5(4:3), DOI 10.3823/283.
    15. Shaker, Amr, Aboshanab*, Khaled, Mabrouk Aboulwafa, Mohammad, Hassouna, Nadia (2014) Plasmid-carried macrolides target site modification erm and efflux msr genes in some Staphylococcus spp. from lower respiratory tract infected patients. Archives of Clinical Microbiology, 5(5:1), DOI 10.3823/284
    16. Noha A. Kamel,  Mohammad M. Aboulwafa, Wafaa N. El-tayeb, Khaled M. Aboshanab* (2014) Antibiotic resistance pattern of aerobic bacteria isolated from patients with diabetic foot ulcers in Egypt. African Journal of Microbiology research. 8(31):2947-2954. DOI:10.5897/AJMR2014.6909.
    17. Masarra Mohammed Sakr, Mohammad Mabrouk Aboulwafa, Khaled Mohamed Anwar Aboshanab*, Nadia Abdel-Haleem Hassouna (2014) Screening and preliminary characterization of the quorum quenching 1 activity of some Bacillus isolates from soil against clinically isolated Pseudomonas aeruginosa homoserine lactones. Malaysian Journal of Microbiology (MJM). 10(2), pp. 80-91
    18. Aboshanab M. Khaled*, Okba M. Nisreen, , El-banna S, Tarek, Abd El-Aziz A. Ahmed (2014) Identification of Genes Putatively Involved in the Biosynthesis of Antitubercular Peptide in Streptomyces ribosidificus NRRL B-11466. British Biotechnology Journal, 4(1):40-50, ISSN: 2231–2927. http://www.sciencedomain.org/review-history.php?iid=282&id=11&aid=2381
    19. Okba M. Nisreen, Aboshanab M. Khaled*, El-banna S, Tarek, Abd El-Aziz A. Ahmed (2013) Isolation, heterologous expression and gene duplication of certain ribostamycin biosynthetic genes from Streptomyces ribosidificus NRRL B-11466. Archives of Clinical Microbiology, 4 (6). doi: 10.3823/275
    20. Samira M. Hamed, Khaled M. A. Aboshanab*, Walid F. Elkhatib, Mohamed S. Ashour (2013). Aminoglycoside Resistance Patterns of Certain Gram Negative Uropathogens Recovered from Hospitalized Egyptian Patients. British Microbiology Research Journal 3(4): 3(4): 678-691.
    21. Noha Salah, Khaled Aboshanab*, Mohammad Aboulwafa, Nadia Hassouna (2013) PHB production in Azomonas, Acinteobacter and Bacillus species: Isolation, Screening and Identification. Archives of Clinical Microbiology. 4(5) 2013. http://imedpub.com/ojs/index.php/acmicrob/article/view/622
    22. Noha Salah, Khaled Aboshanab*, Mohammad Aboulwafa, Nadia Hassouna (2013) Optimization of bioplastic (Poly-β-hydroxybutyrate) production by a promising Azomonas macrocytogenes bacterial isolate P173. African Journal of Microbiology Research.7(42):5025-5035. DOI: 10.5897/AJMR2013.6060
    23. Masarra M. Sakr, Khaled M. Aboshanab*, Mohammad M. Aboulwafa, Nadia A. Hassouna (2013). Characterization and Complete Sequence of Lactonase Enzyme from Bacillus weihenstephanensis Isolate P65 with Potential Activity against Acyl Homoserine Lactone Signal Molecules. Biomedical Research International. 2013: 1-10, Article ID 192589. http://dx.doi.org/10.1155/2013/192589.
    24. Noha A. Kamel, Khaled M. Aboshanab*, Mohammad M. Aboulwafa, Wafaa N. El-tayeb (2013) Plasmid Mediated Extended Spectrum Beta-Lactamase producing strains of Enterobacteraceae Isolated from Diabetic Foot Infections in Egypt. Arch. Clinical microb. 4(4):1-8
    25. Ahmad M. Abbas, Mohammad M. Aboulwafa*, Khaled M. Aboshanab, and Nadia A. Hassouna (2011) Optimization of culture conditions for transformation of vitamin D3 to calcitriol by Actinomyces hyovaginalis isolate A11-2. Arch. Clinical microb. 2(6):1-10. doi: 10:3823/242:
    26. Ahmad M. Abbas; Khaled M. Aboshanab, Mohammad M. Aboulwafa* and Nadia A. Hassouna (2011) Actinomyces hyovaginalis: A novel bacterial isolate with transforming activity of vitamin D3 to 1α, 25-dihydroxyvitamin D3. J. Am. Science, 7(9): 231-237.
    27. Aboshanab KM* (2010) Isolation, recombinant expression and characterization of the dprA gene product in Streptomyces rimosus NRRL 2455. African J. of Microbiology Research, 4(10): 915-922

    B. Local publications:

     

    1. Elgendy N, K Aboshanab KM, M Yassien, M Aboulwafa, N Hassouna (2021). Scaling up, Kinetic modeling, and Economic analysis of poly (3-hydroxybutyrate) production by Bacillus cereus isolate CCASU-P83.Archives of Pharmaceutical Sciences Ain Shams University 5 (1), 158-170. DOI: 10.21608/aps.2021.76831.1061
    2. Amr Bishr; Khaled M. Aboshanab; Mahmoud Yassien; Nadia A. Hassouna (2019). Macrolide resistance pattern of staphylococci collected from hospitalized patients in Egypt. Archives of Pharmaceutical Sciences Ain Shams University, 2019; Vol. 3(2):285-293.  https://dx.doi.org/10.21608/aps.2019.17391.1014
    3. Salma M Abdelaziz; Khaled M. Aboshanab; Mahmoud Yassien; Nadia A. Hassouna (2019). Antimicrobial resistance patterns of MDR Staphylococcus aureus clinical isolates involved in the lower respiratory tract infections in Egypt. Archives of Pharmaceutical Sciences Ain Shams University, 2019; Vol. 3(2):294-304.  https://dx.doi.org/10.21608/aps.2019.17391.1014
    4. Yomna N. Elkholy; Walid Faisal Elkhatib; Khaled M. Aboshanab; Mohammad Aboulwafa; Nadia A. Hassouna (2019). Evaluation of antimicrobial activity and in vitro safety of the methanolic extract of Streptomyces manipurensis soil isolate H21 for potential industrial applications. Archives of Pharmaceutical Sciences Ain Shams University, 2019; Vol. 3(1):1-10.  https://dx.doi.org/10.21608/aps.2019.20201
    5. Asmaa A. Ibrahim, Khaled M. Aboshanab*, Mahmoud A. Yassien, and Nadia A. Hassouna (2017).  Improvement of paromomycin production by Streptomyces rimosus subsp paromomycinus NRRL 2455 using gamma irradiation mutagenesis. Archives of Pharmaceutical Sciences Ain Shams University, 2017; Vol. 1(2):26-30.  DOI: 10.21608/aps.2017.11017
    6. Manar M. Ahmeda, and Yasser M. Ragabb, and Khaled M. Aboshanab* (2017). A large soluble domain of the Staphylococcus aureus ESAT-6 Virulence Factor EsaA is stable in the absence of its cognate transmembrane domains. Archives of Pharmaceutical Sciences Ain Shams University, 2017; Vol. 1(2):39-45.  DOI: 10.21608/aps.2017.11025
    7. Ahmed S. Abu Zaid, Khaled M. Aboshanab*, Mahmoud A. Yassien, and Nadia A. Hassouna (2017). Improvement the production of cytotoxic metabolites by Streptomyces griseus KJ623766. Archives of Pharmaceutical Sciences Ain Shams University, 2017; Vol. 1(2):31-38. DOI: 10.21608/aps.2017.11022
    8. Amira A. Abdelbaset, Aboshanab, Khaled M, Mohammad M. Aboulwafa, Hala A. Farrag* (2015). Profiles of Lipase and Protease Enzymatic activities and antimicrobial resistance of some bacterial isolates recovered from blood samples. Al_azhar J. Of Pharmaceutical Sciences.51: 118-134, ISSN 1110-1644.
    9. Aboshanab KM* (2010) Isolation, Sequencing and Annotation of three genes putatively involved in capreomycidine biosynthesis in Streptomyces ribosidificus NRRL B-11466. Egy. J. of Medical Microbiology, 19(4): 63-74.
    10. Aboshanab KM* (2010) Identification of both neoQ and neoB gene products involved in the biosynthesis of neomycin in Streptomyces fradiae BUWKH 66278. Egy.J. Biotech. 36: 1-15.
    11. Aboshanab KM* (2010) Cloning, expression and knock-out of ribE gene involved in the biosynthesis of Ribostamycin in Streptomyces ribosidificus NRRL B-11466. Egy. J. of Medical Microbiology, 19(1): 47-58.
    12. Aboshanab KM* (2009) Formation, Regeneration and Efficient Plasmid Transformation of Protoplasts of the major 2-deoxystreptamine aminoglycoside producers. Egy. J. biotechnology, 33: 66-78.

  • Research Groups

  • Projects

  • Email

    khaledaboshanab@pharm.asu.edu.eg

  • Link of personal website

    https://pharma.asu.edu.eg/ar/page/12

  • CV

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