Design and Synthesis of Morpholine Based Compounds Targeting PI3K for Anti-cancer Activity

  • Summary

    Cancer is one of the worldwide leading causes of death accounting for nearly 10 million deaths in 2024. Due to the increased resistance to conventional anti-cancer drugs, investigating novel targets for this disease is found to be crucial. Phosphatidylinositol-3 kinase (PI3K) is established as one of the promising targets for fighting this disease. Our aim of work is to develop small molecule PI3K inhibitors and evaluate their biological activity based on our previous expertise in the field of anti-cancer drug design, molecular modeling, organic synthesis skills and biological evaluation techniques. 

  • Achievements


  • List of Publications from the Project


  • Partners

  • Project Members

  • Project Leaders

  • Project PI

    Ahmed Mohamed Marie

  • Faculty

    Faculty of Pharmacy

  • Research Group

  • Funding Agency

    Academy of Scientific Research & Technology (ASRT)

  • Funding Program

    Research Grants

  • Start Date

    2026-01-06

  • End Date

    2027-01-06

  • Sustainable Development Goals (SDGs)

    • 1: No Poverty
    • 2: Zero Hunger
    • 3: Good Health and Well-being
    • 8: Decent Work and Economic Growth
    • 9: Industry, Innovation and Infrastructure

  • Project website