developing a biomarker predictor of brain plasticity mechanism post-stroke as a guide for the choice of the paradigm of non -invasive brain stimulation

Summary

To study the presence of interhemispheric inhibition from the healthy hemisphere on the lesioned hemisphere in chronic stroke, this will help determine whether the positive neuroplasticity and hence recovery is developing from the healthy hemisphere or the healthy hemisphere is inhibiting, thus hindering the recovery of the lesioned hemisphere 

To recognize the different clinical and radiological biomakers of stroke that correlate with the development of the interhemispheric inhibition such as clinical and functional severity, presence of specific neurological signs such as neglect or sensory inattension, and the exact site and size of infarction, accordingly, these biomarkers will enable tailoring of the future therapeutic rTMS protocols for each individual 

To correlate the interhemispheric inhibition detected using the TMS with the results of FMRI in chronic stroke, in case of positive correlation, this will support the results of TMS and indirectly reduces the need for a more costly investigation as fMRI

Achievements

List of Publications from the Project

Partners

Project Members

• Tamer Mahmoud ElSayed Roushdy
• Eman Hamid Abd ElDayem

Project Leaders

• Nevine El Nahas
• Fatma Kenawy