Fungal metabolites from Passiflora edulis: An alternative and sustainable source of cytotoxic and antimicrobial natural products

Summary

Natural products offer a potential chance in the control and prevention of various diseases, particularly with the increasing prevalence of drug-resistant infections. Edible plants played a crucial role as a valuable source of natural products owing to their availability, variability, and relatively low price. Endophytic fungi with their species diversity are capable of production of a variety of bioactive metabolites that act as a source of novel pharmaceutically active compounds. Endophytic fungi isolated from these edible plants can be used as a great alternate and sustainable source of bioactive secondary metabolites primarily produced by the plants. Secondary metabolites produced by endophytes possess higher therapeutic and pharmaceutical value. Fungal metabolites are the target of our research for the purpose of finding new useful antimicrobial drugs; particularly, when Antimicrobial Resistance (AMR) has exceeded all limits after many world’s prevailing pandemics. Furthermore, these lead molecules can be obtained abundantly in gram amounts thus solving the supply problem of bioactive natural products.

Achievements

List of Publications from the Project

Partners

Project Members

• Hagar Ashraf
• Ashaimaa moussa
• abdel nasser singab
• Nouran Fahmy

Project Leaders